THE INHIBITION OF PINK1/DRP1-MEDIATED MITOPHAGY BY HYPERGLYCEMIA LEADS TO IMPAIRED OSTEOBLASTOGENESIS IN DIABETES

The inhibition of PINK1/Drp1-mediated mitophagy by hyperglycemia leads to impaired osteoblastogenesis in diabetes

Summary: Impaired bone quality and increased fracture risk are cardinal features of the skeleton Boxer in diabetes mellitus.Hyperglycemia-induced oxidative stress is proposed as a potential underlying mechanism, but the precise pathogenic mechanism remains incompletely understood.In this investigation, osteoblasts under high glucose exhibited heigh

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Discrimination as a predictor of poor mental health among LGBTQ+ people during the COVID-19 pandemic: cross-sectional analysis of the online Queerantine study

Objectives Hair To assess the mental health and experiences of discrimination among lesbian, gay, bisexual, transgender, queer (LGBTQ) people at the start of the COVID-19 pandemic.Design Data come from a cross-sectional online survey targeted at LGBTQ+ people, which collected data on mental health, experiences of discrimination and a number of othe

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Laparoscopic Excision of Coexisting Left Tubal and Right Pseudotubal Pregnancy after Conservative Management of Previous Ectopic Pregnancy with Methotrexate: An Unusual Clinical Entity

Tubal pregnancy concerns 97% of all ectopic pregnancies.Treatment can be either surgical (salpingostomy or salpingectomy) or medical (methotrexate administration).We present a case of a pseudotubal pregnancy after methotrexate 3N treatment of a previous ectopic pregnancy.A37-year-old woman was diagnosed with ectopic pregnancy in the left Fallopian

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